Mar 1, 2017 23:37
7 yrs ago
11 viewers *
German term

AA ad

German to English Medical Medical (general)
Verordnung/Therapievorschlag: Dermatop Basis Creme ***AA ad***

I don't speak Latin, but I am fairly certain that it means "ana partes aequales ad", "zu gleichen Teilen bis". I found it in Beckers.

I would like to know the proper English expression for it. I can't quite come up with it.

Any suggestions?
Proposed translations (English)
3 +1 in equal quantities

Discussion

Jacek Kloskowski Mar 3, 2017:
Not sure what do you mean, As I understand, Dermatop(r) is a marketing name for an active ingredient called "Prednicarbate":

"A Review of Prednicarbate (Dermatop®)
(...)
Prednicarbate is a nonhalogenated corticosteroid that is used in the treatment of inflammatory skin diseases, for example, atopic dermatitis.(...)Prednicarbate is a nonhalogenated, double-ester derivative of prednisolone. Modification to the prednisolone molecule has resulted in a molecule that causes the suppression of inflammation, but maintains low skin atrophy potential."


As such, there can be various formulations of the drug:

"(...)
Clinical Efficacy
Several German and Spanish studies have reported the effectiveness of prednicarbate in a variety of formulations at a strength of 0.25%, for the treatment of dermatitis.8
In two multicenter, randomized, double-blind, parallel group studies (see Table 1), Hanifin et al.9 compared prednicarbate 0.1% emollient cream with both the emollient cream vehicle and betamethasone valerate 0.1% cream"


http://www.skintherapyletter.com/2004/9.10/2.html
Jacek Kloskowski Mar 3, 2017:
@Cilian, After reading into this, there may be two substances:

1) Dermatop(r)
2) Cream base.

As I understand, sometimes brand name topical drugs with active ingredient are thinned with base. For exmaple, look in the "Merkblatt "from the link below; under the section named "Cortison", where they also mention "Dermatop(R)". Just below that there is an example of recommended medication regimen which explains thinning of Alafson(R) creme with cream base in different proportions:

http://www.fachklinik-sylt.de/media/downloads/nd_merkblatt.p...
Cilian O'Tuama Mar 3, 2017:
@JackMark As it stands, how can it mean equal amounts if there is only one substance?
And how does the 'ad' fit in?
It's normally used to denote 'make up to a total quantity of x', so it needs to be followed by a number+unit (not a time of day).
Jacek Kloskowski Mar 3, 2017:
No, it does make sense. Basiscreme is the "cream base' mixed with active ingredients, I guess in this case Dermatop:

Die Basiscreme DAC liegt als Öl-in-Wasser-Emulsion (O/W-Emulsion) vor. Sie ist eine amphiphile Creme, die unbegrenzt lipophile Substanzen oder hydrophile Substanzen aufnehmen kann. Durch Einarbeitung von lipophilen Stoffen kommt es nach Erreichen der Kapazitätsgrenze des O/W-Emulgators (Macrogol-1000-glycerolmonostearat) zur Phaseninversion, wobei die lipophile Phase die Funktion des Dispersionsmittels übernimmt und die W/O-Emulgatoren (Glycerolmonostearat 60, Cetylalkohol) die Filmbildung dominieren.

https://de.wikipedia.org/wiki/Basiscreme_DAC

A medication's potency often is changed with its base. For example, some topical steroids will be classified one or two strengths higher when moving from cream to ointment. As a rule of thumb, an ointment base is more occlusive and will drive the medication into the skin more rapidly than a solution or cream base.

https://en.wikipedia.org/wiki/Topical_medication
Sonja Poeltl (asker) Mar 3, 2017:
No, All it says after it is "(abends)".
Cilian O'Tuama Mar 2, 2017:
Doesn't make sense as it stands. Is there a second substance and a quantity/number missing?

Proposed translations

+1
24 mins

in equal quantities

SYMBOLS AND ABBREVIATIONS USED IN PRESCRIPTION

aa is the abbreviation of ana partes aequales (in equal quantities), expressing “the substances are in equal quantities”.

http://www.medpharm-sofia.eu/files/DIR 5/Section 9/Structure...

--------------------------------------------------
Note added at 28 mins (2017-03-02 00:06:08 GMT)
--------------------------------------------------

ana (ˈeɪnə; ˈɑːnə)
adv
(Pharmacology) pharmacol obsolete (of ingredients in a prescription) in equal quantities. Abbreviation: aa

http://www.thefreedictionary.com/ana
Peer comment(s):

agree Fimbrethill : mf ung proz
2056 days
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