Glossary entry

English term or phrase:

control at 0.05

Italian translation:

contenere a un livello di 0,05

Added to glossary by Chiara Gavasso
Feb 4, 2022 15:07
2 yrs ago
23 viewers *
English term

control at 0.05

English to Italian Medical Mathematics & Statistics statistical analysis in clinical trials
A nominal p-value of less than 0.02499 (2-sided) will be needed to declare statistical significance for the final primary analysis of each [drug] dose group when compared to placebo to *control the study-wise type I error rate at 0.05*.

Mi sto scervellando su "control at 0.05", ma confesso di comprendere a fatica la frase intera, se non a grandissimissime linee. So che si parla di "controllo del FWER", ma usare "controllare" qui non mi convince, ma forse sbaglio. Ho pensato, anche considerando che si parla di significatività statistica, a "fissare il tasso di errore di I tipo nello studio a 0,05": potrebbe avere senso?
Proposed translations (Italian)
4 +1 contenere a un livello di 0,05

Proposed translations

+1
6 hrs
Selected

contenere a un livello di 0,05

L'errore di tipo I sono i falsi positivi.
... per contenere il tasso di errore di tipo I relativo allo studio a un livello di 0,05.

Provided that statistical assumptions are met, the maximum Type I error rate is simply the α level chosen for the test (conventionally .05).
https://journals.sagepub.com/doi/10.1177/2515245920985137
La probabilità alfa è la probabilità di commettere un errore di tipo I. è abituale fissarla in a=0,05, vale a dire una probabilità del 5%.
https://www.scientific-european-federation-osteopaths.org/gl...

https://www.investopedia.com/terms/t/type_1_error.asp
https://toolbox.eupati.eu/glossary/errore-di-tipo-i/?lang=it...
Peer comment(s):

agree Claudia Sorcini
12 hrs
Grazie! :)
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "grazie mille, EleoE, mi hai illuminato!"

Reference comments

51 mins
Reference:

other examples

Thromobosis and Targeted Synthetic DMARDs: Is the Risk ...https://arthros.org › downloads › Thromobosis-an...PDF
statistical significance for baricitinib 4 mg vs. adalimumab or baricitinib 4 mg vs. placebo with ****studywise error rate strongly controlled at α=0.05*** for ...

Baricitinib in patients with inadequate response or intolerance ...https://eprints.whiterose.ac.uk › 88.full.pdfPDF
by M Dougados · 2017 · Cited by 279 — week 24 was reduced with baricitinib versus placebo. Rates of adverse events during the ... ***strong control for the familywise error rate****. Treatment compari-.


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Note added at 53 mins (2022-02-04 16:00:40 GMT)
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Family-wise error rate - Wikipediahttps://en.wikipedia.org › wiki › Family-wise_error_rate
The reason why this procedure controls the family-wise error rate for all the m hypotheses at level α in the strong sense is, because it is a closed testing ...

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Note added at 55 mins (2022-02-04 16:02:28 GMT)
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False Discovery Rate - Columbia University's Mailman School ...https://www.publichealth.columbia.edu › research › fals...
In other words, we want the probability of a type I error, or a false positive, ... The commonly used Bonferroni correction controls the FWER. If we test ...


FWIW I always find "control" difficult to translate, does it mean "monitor", "keep at/maintain" but then I don't generally translate this type of text:)

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Note added at 58 mins (2022-02-04 16:05:37 GMT)
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anything here?:


Ministero della Salute - Agenzia Italiana Farmacohttp://www.agenziafarmaco.gov.it › 111.20824.1...PDF
The trial has been properly designed and carried out in ... an abbreviation for the control of the family-wise type I error in the strong sense, i.e., ...

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Note added at 1 hr (2022-02-04 16:08:46 GMT)
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Correzione Bonferroni 2021 - Wikit.wikihttps://www.wikit.wiki › blog › Bonf...· Translate this page
4 Dec 2021 — Da segnalare che la correzione di Bonferroni ****controlla il tasso di errore family-wise ****(ovvero relativo all'ipotesi nulla che è vera per ...

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Note added at 1 hr (2022-02-04 16:27:10 GMT)
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Strumenti statistici per l'analisi di dati geneticihttp://www.genopomii.unina.it › genohort › filesPDF
16 May 2014 — Test multipli e controllo dell'errore. Selezione di geni differenzialmente espressi. Microarray. L'idea di fondo `e usare le informazioni ...
210 pages
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